BIGG

Red blood cell specifications for patients with hemoglobinopathies: a systematic review and guideline

Compernolle, Veerle; Chou, Stella T; Tanael, Susano; Savage, William; Josephson, Cassandra D; Odame, Isaac; Hogan, Christopher; Denomme, Gregory; Shehata, Nadine.

Transfus; 58 (6), 2018

BACKGROUND Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β‐thalassemia. Alloimmunization, a well‐documented complication of transfusion, increases the risk of delayed hemolytic transfusion reactions, complicates crossmatching and i...

Anemia de Células Falciformes, Transfusión de Eritrocitos/22074, Hemoglobinopatías/terapia, Reacción a la Transfusión/prevención & control, Reacción a la Transfusión, Talasemia beta/terapia, Anemia de Células Falciformes/terapia, Eritrocitos/metabolismo, Anemia de Células Falciformes/tratamiento farmacológico, Transfusión de Eritrocitos, Isoanticuerpos/uso terapéutico, Isoantígenos/uso terapéutico

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Sickle cell disease: managing acute painful episodes in hospital

This guideline covers managing acute painful sickle cell episodes in children, young people and adults who present at hospital, from presentation until when they are discharged. It aims to reduce variation in how acute episodes are managed in hospital, focusing on effective, prompt and safe pain relief. ...